Glutathione — Dr. Rawls’ Ratings
Efficacy: 4 stars
Safety: 5 stars
Cost: 1 out of 5 dollar signs
Ways to Administer: oral powder, liquid, and capsules. Glutathione can also be administered intravenously.
Bottom Line: Glutathione is a supportive therapy that can boost your antioxidant profile, assist in detoxification, and minimize Herxheimer reactions.


Glutathione is a potent antioxidant derived from the amino acids cysteine, glutamate, and glycine; it’s used by all the cells in your body for a variety of purposes. It plays a key role in the body’s ability to detoxify.

The most common forms of glutathione are reduced and liposomal. During my Lyme recovery journey, I developed a significant head and hand tremor, and I was able to eliminate it by taking reduced glutathione powder mixed with coconut milk twice daily. Within two weeks, the tremors were gone.


There’s been a question about whether we absorb glutathione when taken orally, but research suggests certain forms of the compound are indeed absorbed by the body. We don’t get 100% absorption because some of it’s broken down in the gastrointestinal tract, but we can augment our body’s glutathione through supplementation.


The potential for harm with glutathione is likely quite low and could make a great addition to your recovery protocol, particularly when trying to manage Herxheimer reactions.


In my experience, reduced glutathione mixed with coconut milk is a more cost-effective option, however, some patients may feel they get better results from the liposomal form, which tends to be a pricier option.

Dr. Bill Rawls Treatment Guide

Dr. Bill Rawls’ Treatment Guide

Want to see more Lyme disease treatment ratings? See What Dr. Rawls has to say about popular treatments and therapies in his Lyme Disease Treatment Guide.

Dr. Rawls is a physician who overcame Lyme disease through natural herbal therapy. You can learn more about Lyme disease in Dr. Rawls’ new best selling book, Unlocking Lyme.
You can also learn about Dr. Rawls’ personal journey in overcoming Lyme disease and fibromyalgia in his popular blog post, My Chronic Lyme Journey.