Native to Tibet, Cordyceps is a fungal species that grows on a specific type of caterpillar during specific times of the year. Historically, its value was equal in weight to gold, and it was specifically reserved for emperors and royalty. Today, fortunately, high-quality Cordyceps can be easily cultivated, and its wonderful benefits are available to anyone.
Cordyceps offers properties of immunomodulation and resistance to any type of stress. It protects mitochondria and is anti-fatigue. It is regularly used by Chinese and Russian athletes.
In laboratory studies, Cordyceps was found to reduce heart muscle oxygen consumption and improve aerobic activity. In traditional herbal medicine, it is often used as a kidney tonic. Cordyceps specifically stimulates NK cells and macrophage activity and also enhances cellular immunity. At the same time, it decreases inflammatory cytokine cascades and therefore decreases tissue damage.
Cordyceps also offers antiviral and antibacterial properties. Provides coverage against Bartonella and Mycoplasma.
Suggested dosage: 1-3 grams (1000-3000 mg) whole mushroom Cordyceps powder or 400-800 mg extract (standardized to >7% Cordyceptic acid is preferred) two to three times daily.
Side effects: Mild nausea can occur, but in general, side effects are rare, even with higher doses. Allergic reactions are rare.
1. Nakamura K, Shinozuka K, Yoshikawa N. Anticancer and antimetastatic effects of cordycepin, an active component of Cordyceps sinensis. J Pharmacol Sci. 2015;127(1):53-56.
2. Zhang HW, Lin ZX, Tung YS, et al. Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease. Cochrane Database Syst Rev. 2014;12:CD008353.
3. Tuli HS, Sharma AK, Sandhu SS, Kashyap D. Cordycepin: a bioactive metabolite with therapeutic potential. Life Sci. 2013;93(23):863-869. Epub 2013 Oct 10.
4. Yue K, Ye M, Zhou Z, Sun W, Lin X. The genus Cordyceps: a chemical and pharmacological review. J Pharm Pharmacol. 2013;65(4):474-493. Epub 2012 Oct 23.
5. Chang ST, Wasser SP. The role of culinary-medicinal mushrooms on human welfare with a pyramid model for human health. Int J Med Mushrooms. 2012;14(2):95-134.
6. Ng TB, Wang HX. Pharmacological actions of Cordyceps, a prized folk medicine. J Pharm Pharmacol. 2005;57(12):1509-1519.
7. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of an ancient Chinese herbal medicine: Cordyceps sinensis: part I. J Altern Complement Med. 1998;4(3):289-303.
8. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: part II. J Altern Complement Med. 1998;4(4):429-457. Review.
9. Chen CY, Hou CW, Bernard JR, et al. Rhodiola crenulata and Cordyceps sinensis-based supplement boosts aerobic exercise performance after short-term high altitude training. High Alt Med Biol. 2014;15(3):371-379.
10. Yan F, Wang B, Zhang Y. Polysaccharides from Cordyceps sinensis mycelium ameliorate exhaustive swimming exercise-induced oxidative stress. Pharm Biol. 2014;52(2):157-161. Epub 2013 Sep 19.
11. Chen S, Li Z, Krochmal R, Abrazado M, Kim W, Cooper CB. Effect of Cs-4 (Cordyceps sinensis) on exercise performance in healthy older subjects: a double-blind, placebo-controlled trial. J Altern Complement Med. 2010;16(5):585-590.
12. Guggenheim AG, Wright KM, Zwickey HL. Immune Modulation From Five Major Mushrooms: Application to Integrative Oncology. Integr Med (Encinitas). 2014;13(1):32-44.
13. Xiong Y, Zhang S, Xu L, et al. Suppression of T-cell activation in vitro and in vivo by cordycepin from Cordyceps militaris. J Surg Res. 2013;185(2):912-922. Epub 2013 Jul 22.
14. Wang L, Hou Y. Determination of trace elements in anti-influenza virus mushrooms. Biol Trace Elem Res. 2011;143(3):1799-1807. Epub 2011 Feb 8.
15. Shin S, Lee S, Kwon J, et al. Cordycepin Suppresses Expression of Diabetes Regulating Genes by Inhibition of Lipopolysaccharide-induced Inflammation in Macrophages. Immune Netw. 2009;9(3):98-105. Epub 2009 Jun 30.
16. Zhou X, Luo L, Dressel W, et al. Cordycepin is an immunoregulatory active ingredient of Cordyceps sinensis. Am J Chin Med. 2008;36(5):967-980.
17. Jordan JL, Sullivan AM, Lee TD. Immune activation by a sterile aqueous extract of Cordyceps sinensis: mechanism of action. Immunopharmacol Immunotoxicol. 2008;30(1):53-70.