Sarsaparilla is native to South America, but Smilax species with medicinal benefit are common around the world. Sarsaparilla is thought to bind endotoxins. Endotoxins are the debris created when pathogenic bacteria are killed off.
Sarsaparilla also offers antibacterial and antifungal properties. It is commonly used in Lyme disease protocols. Traditionally, it is used for treatment of psoriasis and other skin conditions.
Also, sarsaparilla has been used traditionally for treatment of syphilis (another spirochete, like Borrelia). Sarsaparilla increases bioavailability of other herbs and enhances benefit (synergist). Other beneficial properties include potent anti-inflammatory and antioxidant properties. It also enhances immune function.
Sarsaparilla is a synergist for Lyme protocols and important for restoration of gastrointestinal function.
Suggested dosage: 200-1000 mg of standardized root extract two to three times daily.
Side effects: Uncommon. Sarsaparilla is generally well tolerated.
1. Tse TW. Use of common Chinese herbs in the treatment of psoriasis. Clin Exp Dermatol. 2003;28(5):469-475.
2. Jiang J, Wu F, Lu J, Lu Z, Xu Q. Anti-inflammatory activity of the aqueous extract from Rhizoma smilacis glabrae. Pharmacol Res. 1997;36(4):309-314.
3. Xu S, Shang MY, Liu GX, et al. Chemical constituents from the rhizomes of Smilax glabra and their antimicrobial activity. Molecules. 2013;18(5):5265-5287.
4. Itharat A, Srikwan K, Ruangnoo S, Thongdeeying P. Anti-Allergic Activities of Smilax glabra Rhizome Extracts and Its Isolated Compounds. J Med Assoc Thai. 2015;98 Suppl 3:S66-S74.
5. Lu CL, Zhu W, Wang M, Xu XJ, Lu CJ. Antioxidant and Anti-Inflammatory Activities of Phenolic-Enriched Extracts of Smilax glabra. Evid Based Complement Alternat Med. 2014;2014:910438. Epub 2014 Nov 11.
6. Jiang J, Xu Q. Immunomodulatory activity of the aqueous extract from rhizome of Smilax glabra in the later phase of adjuvant-induced arthritis in rats. J Ethnopharmacol. 2003;85(1):53-59.